SS-31
Full description
SS-31 (Elamipretide) is a mitochondrially targeted peptide that protects cellular structure, optimizes ATP energy production, and eliminates oxidative stress at its cellular source.
What is it used for? (Primary Research Applications)
SS-31 is a synthetic tetrapeptide engineered to penetrate the inner mitochondrial membrane and selectively bind to cardiolipin. Main research applications include:
- Restoration of ATP Production: Restores mitochondrial cristae structure, optimizing electron transport chain efficiency.
- Reactive Oxygen Species (ROS) Scavenging: Neutralizes free radicals directly at their primary site of formation, preserving mitochondrial DNA integrity.
- Cardioprotection & Renal Support: Studied in ischemia-reperfusion models, heart failure, and acute kidney injury for its cell-preserving capacities.
- Neuromuscular Recovery & Anti-Aging: Mitigates age-related muscular weakness and neurodegenerative decline caused by mitochondrial dysfunction.
Long Description & Mechanism of Action
Unlike conventional antioxidants that act non-specifically in the cytoplasm, SS-31 concentrates exclusively in the inner mitochondrial membrane. By stabilizing cardiolipin, it prevents the structural breakdown of mitochondria brought on by aging or disease.
Technical Specifications
- Alternative Names: Elamipretide, MTP-131
- Sequence: D-Arg-Dmt-Lys-Phe-NH2
- Molecular Formula: C32H49N9O5
- Purity: ≥ 99% (HPLC)
- Form: Lyophilized powder in sterile vial
Shipping & cold chain
All orders ship with thermally monitored packaging to preserve product integrity in transit.
Storage
Store lyophilized vials between 2°C and 8°C for short-term handling, or frozen at -20°C for long-term preservation.
For research use only.